The fashion world has always had a complicated relationship with body size. For decades, the modeling industry has prized extreme thinness, with sample sizes hovering around zero. But the explosion of GLP-1 medications is introducing a powerful new shortcut to achieving and maintaining that coveted look. These drugs include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound).
A recent Vogue article explores how these weight-loss drugs are influencing casting calls, runway shows, and the overall aesthetic of the industry. What was once achieved through rigorous dieting, exercise, or more extreme measures now has a pharmaceutical assist for many.

