The answer is yes, according to a co-star.
When Us Weekly asked James Pickens Jr. (a.k.a. Grey’s Dr. Richard Webber) on February 7 if [Katherine] Heigl is leaving the medical drama, he said, “Yes, she is.” And he continued, “Wherever Katherine goes, I wish her nothing but the best.”
Her outspoken BFF, [T.R.] Knight, 35. “He’s going too,” Pickens told Us at the NAACP Awards luncheon in Beverly Hills. “He just wanted to pursue other career paths.”
“He complains to Katherine all the time,” a set source has said of Knight (with Heigl). “The energy on set will be much better when he’s gone.”
I stopped watching the show a few seasons ago when everyone started sleeping with each other. But this is (probably) huge news to fans still devoted to the show. I have always like Heigl (ever since the days of “Roswell”) so it will be interesting to see where she lands next.
2/18 Update: According to Shonda Rhimes, the two actors aren’t leaving the show.